Self-assembling micelle-like nanoparticles based on phospholipid–polyethyleneimine conjugates for systemic gene delivery
نویسندگان
چکیده
منابع مشابه
Lipid-like Self-Assembling Peptide Nanovesicles for Drug Delivery
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Objective(s): PEI based nanoparticle (NP) due to dual capabilities of proton sponge and DNA binding is known as powerful tool for nucleic acid delivery to cells. However, serious cytotoxicity and complicated conditions, which govern NPs properties and its interactions with cells practically, hindered achievement to high transfection efficiency. Here, we have tried to optimize the properties of ...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2009
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2008.09.079